Computational Biology is an important part of Coronavirus research. There are large, established distributed computing projects specifically working on COVID-19 research: Folding@Home and Rosetta@Home are two of the oldest and best-established projects. But both of those projects have not historically been made available to run on mobile devices with Arm processors.
We are actively working to provide Arm support for these Coronavirus distributed computing applications. This will make them available on the Neocortix Scalable Compute platform, and also on the BOINC platform running on Arm devices, and on other Arm-based platforms such as Raspberry Pi, MiniNodes and Packet.com.
With the recent COVID-19 outbreak, Rosetta@Home has been used to predict the structure of proteins important to the disease as well as to produce new, stable mini-proteins to be used as potential therapeutics and diagnostics, like the one displayed below which is bound to part of the COVID-19 spike protein:
From March 17-31, 2020, Neocortix worked with teams from Rosetta@Home, Arm, MiniNodes, Linaro, and Packet.com to create, verify and test a Linux-on-Arm build of Rosetta. On March 31, the Rosetta team published the new Linux-on-Arm build.
Since then, the group effort has shifted to deployment onto Arm devices. As of April 8, there were over 200 Arm devices contributing to the Rosetta project, with over 500,000 credits earned. On April 8, Neocortix completed its upgrades for temperature and battery monitoring, and is now ramping up deployment onto its existing network of 3000 mobile devices, soon to be followed by up to 42,000 volunteer devices from our PhonePaycheck waiting list.
The spike of the SARS-CoV-2 virus (shown below) is a major target for designing therapeutics to combat the COVID-19 disease.
On April 1, 2020, the Folding@Home team began its engagement with our extended team to create a Linux-on-Arm build of Folding@Home. Neocortix has already completed a Linux-on-Arm build of Gromacs, which is an important component of Folding@Home. We are now engaging with the Gromacs-core team to assist with a Linux-on-Arm build of the Folding@Home core.
For a detailed description of the project, please see our blog: "Multi-Company Collaboration For Coronavirus Research On Arm Devices".
We are grateful for support and collaboration from the following companies and organizations: